Ensovi Partners with Ginkgo Bioworks to Advance Sustainable Biomanufacturing

Ensovi Inc., a company specializing in efficient, cell-free biomanufacturing, has joined forces with Ginkgo Bioworks, a leader in cell programming and biosecurity, to revolutionize carbon dioxide (CO2) utilization in biomanufacturing. Ensovi’s technology aims to convert waste CO2 into valuable organic chemicals through an innovative, cell-free biosynthesis approach. The partnership with Ginkgo will harness Ginkgo Enzyme Services to optimize this carbon fixation process and expand the range of applications.
The chemical industry is increasingly seeking sustainable and cost-effective manufacturing alternatives to reduce carbon emissions and decarbonize supply chains. Ensovi’s approach offers a promising solution by utilizing CO2 as a feedstock for biomanufacturing. This method has the potential to lead to carbon-neutral or even carbon-negative manufacturing processes, reducing feedstock costs and environmental impact while offering practical alternatives for companies dealing with expensive CO2 waste streams.
Ensovi has already developed highly efficient and scalable systems for recycling enzyme cofactors, providing the necessary biochemical energy for biomanufacturing organic chemicals from CO2 at a competitive cost. By collaborating with Ginkgo, Ensovi aims to expedite the discovery and design of bioengineered enzymes that are market-ready. These enzymes from the partnership will play a crucial role in extending the capabilities of Ensovi’s cell-free biomanufacturing platform, enabling a broader application in fine and commodity chemical manufacturing.
Ginkgo Bioworks offers comprehensive end-to-end capabilities for enzyme discovery, optimization, and production. Leveraging their proprietary gene database containing over 2 billion genes and advanced machine learning tools, they can identify novel enzyme activities and optimize enzyme function and stability. Ginkgo provides access to production hosts for enzyme expression, as well as the development of optimized fermentation processes and scale-up services. Their services span various industries, including agriculture, biopharmaceuticals, government, industrials, nutrition, and wellness.
Richard Harrison, co-founder and CEO of Ensovi, emphasized the potential of their modular cell-free system in transforming CO2, a primary greenhouse gas emitted through human activities, into a wide range of valuable materials. He stated, “Our collaboration will draw on Ginkgo’s extensive enzyme discovery and design capabilities, allowing us to accelerate our continuous process of pathway discovery and enzyme optimization to further reduce costs and expand our supported product portfolio.”